High-dose chemotherapy with autologous peripheral blood stem cell support for recurrent primary AFP-producing intracranial germinoma

نویسندگان

  • Carsten Ziske
  • Jörg Mezger
  • Carlos Jiménez
  • Rolf Kleinschmidt
  • Hendrik Pels
  • Uwe Schlegel
  • Ingo G.H. Schmidt-Wolf
چکیده

We report of a 34-year old man with second intracranial relapse of a suprasellar germinoma. Despite of extensive pretreatment with radiation and conventional chemotherapy relapse occurred and was treated with sequential high-dose chemotherapy followed by transfusion of autologous peripheral stem cells. The high-dose chemotherapy course was complicated by refractory derailment of pineal gland insufficiency. The patient achieved a complete remission after high dose chemotherapy which lasted for 13 months. Subsequently, he developed a third relapse and died.

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عنوان ژورنال:

دوره 1  شماره 

صفحات  -

تاریخ انتشار 2003